Selected publications in reverse chronological order (*corresponding author). Read a full list of publications.

Ashinoff BK, Buck J, Woodford M, Horga G . "The effects of base rate neglect on sequential belief updating and real-world beliefs." PLoS Comput Biol. 2022 Dec;18(12): e1010796. Download Publication (PDF)

Al Haddad R, Chamoun M, Tardif CL, Guimond S, Horga G, Rosa-Neto P, Cassidy CM. “Normative Values of Neuromelanin-Sensitive MRI Signal in Older Adults Obtained Using a Turbo Spin Echo Sequence.” J Magn Reson Imaging. 2022 Nov. doi: 10.1002/jmri.28530. Online ahead of print.PMID: 36373996. Download  Publication (PDF)

Mihali A, Broeker M, Ragalmuto F, Horga G. "Introspective inference counteracts perceptual distortion." bioRxiv. 2022 Sept. doi: Download Publication (PDF).

Singletary NM, Gottlieb J, Horga G. "A neural substrate for Bayesian integration in human parietal cortex." bioRxiv. 2021 Oct. doi: Download Publication (PDF).

Wengler K, Cassidy C, van der Pluijm M, Weinstein JJ, Abi-Dargham A, van de Giessen E, Horga G. "Cross-Scanner Harmonization of Neuromelanin-Sensitive MRI for Multisite Studies," J Magn Reson Imaging. 2021 Oct;54(4):1189-1199. doi: 10.1002/jmri.27679. Epub 2021 May 6. PMID: 33960063. Download Publication (PDF)

Ueno F, Iwata Y, Nakajima S, Caravaggio F, Rubio JM, Horga G, Cassidy CM, Torres-Carmona E, de Luca V, Tsugawa S, Honda S, Moriguchi S, Noda Y, Gerretsen P, Graff-Guerrero A. "Neuromelanin accumulation in patients with schizophrenia: A systematic review and meta-analysis." Neurosci Biobehav Rev. 2022 Jan;132:1205-1213. doi: 10.1016/j.neubiorev.2021.10.028. Epub 2021 Oct 27. PMID: 34718049; PMCID: PMC9059704. Download Publication (PDF)

Salzman G, Kim J, Horga G, Wengler K. "Standardized Data Acquisition for Neuromelanin-sensitive Magnetic Resonance Imaging of the Substantia Nigra," J Vis Exp. 2021 Sep 8;(175). doi: 10.3791/62493.PMID: 34570093 Download Publiction (PDF)

Horga G, Wengler K, Cassidy CM. "Neuromelanin-Sensitive Magnetic Resonance Imaging as a Proxy Marker for Catecholamine Function in Psychiatry," JAMA Psychiatry. 2021 Jul 1;78(7):788-789. doi: 10.1001/jamapsychiatry.2021.0927. PMID: 34009285. Download Publication (PDF)

Wengler K, Ashinoff BK, Pueraro E, Cassidy CM, Horga G, Rutherford BR. "Association between neuromelanin-sensitive MRI signal and psychomotor slowing in late-life depression," Neuropsychopharmacology. 2021 Jun;46(7):1233-1239. doi: 10.1038/s41386-020-00860-z. Epub 2020 Sep 12. PMID: 32919398; PMCID: PMC8134510. Download Publication (PDF)

Ashinoff BK, Singletary NM, Baker SC, Horga G. "Rethinking delusions: A selective review of delusion research through a computational lens." Schizophr Res. 2021 Mar 3:S0920-9964(21)00065-7. doi: 10.1016/j.schres.2021.01.023. Epub ahead of print. PMID: 33676820; PMCID: PMC8413395. Download Publication (PDF)

Wengler K, Horga G. "The Quest for a Selective Mapping Between Striatal Dopamine Subcircuits and Psychosis Symptoms," Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Nov;5(11):1004-1006. doi: 10.1016/j.bpsc.2020.09.009. PMID: 33161955. Download Publication (PDF)

Cassidy CM, Carpenter KM, Konova AB, Cheung V, Grassetti A, Zecca L, Abi-Dargham A, Martinez D, Horga G. "Evidence for Dopamine Abnormalities in the Substantia Nigra in Cocaine Addiction Revealed by Neuromelanin-Sensitive MRI," Am J Psychiatry. 2020 Nov 1;177(11):1038-1047. doi: 10.1176/appi.ajp.2020.20010090. Epub 2020 Aug 28. PMID: 32854531. Download Publication (PDF)

Wengler K, Goldberg AT, Chahine G, Horga G. Distinct hierarchical alterations of intrinsic neural timescales account for different manifestations of psychosis. Elife. 2020 Oct 27;9:e56151. doi: 10.7554/eLife.56151. PMID: 33107431; PMCID: PMC7591251. Download Publication (PDF)

Wengler K, He X, Abi-Dargham A, Horga G. "Reproducibility assessment of neuromelanin-sensitive magnetic resonance imaging protocols for region-of-interest and voxelwise analyses," Neuroimage. 2020 March;208:116457. Download Publication (PDF)

Horga G, Abi-Dargham A. "An integrative framework for perceptual disturbances in psychosis," Nat Rev Neurosci. 2019 December;20(12):763-778. Download Publication (PDF)

Smith EH, Horga G, Yates MJ, Mikell CB, Banks GP, Pathak YJ, Schevon CA, McKhann GM 2nd, Hayden BY, Botvinick MM, Sheth SA. "Widespread temporal coding of cognitive control in the human prefrontal cortex," Nat Neurosci. 2019 Nov;22(11):1883-1891. Download Publication (PDF)

Clifford M. Cassidy, Fabio A. Zucca, Ragy R. Girgis, Seth C. Baker, Jodi J. Weinstein, Madeleine E. Sharp, Chiara Bellei, Alice Valmadre, Nora Vanegas, Lawrence S. Kegeles, Gary Brucato, Un Jung Kang, David Sulzer, Luigi Zecca, Anissa Abi-Dargham, and Guillermo Horga. "Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain," PNAS. March 12, 2019 116 (11) 5108-5117. Download Publication (PDF)

Seth C. Baker, Anna B. Konova, Nathaniel D. Daw and Guillermo Horga. "A distinct inferential mechanism for delusions in schizophrenia," Brain: A Journal of Neurology. 2019 Jan 16: 142; 1797-1812. Download Publication (PDF)

Sulzer D, Cassidy C, Horga G, Kang UJ, Fahn S, Casella L, Pezzoli G, Langley J, Hu XP, Zucca FA, Isaias IU, Zecca L. “Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson's disease.” NPJ Parkinsons Dis. 2018 Apr 10. Download Publication (PDF).

Cassidy CM, Balsam PD, Weinstein JJ, Rosengard RJ, Slifstein M, Daw ND, Abi-Dargham A, Horga G. “A Perceptual Inference Mechanism for Hallucinations Linked to Striatal Dopamine.” Curr Biol. 2018 Feb 19. Download Publication (PDF)

Lehembre-Shiah E, Leong W, Brucato G, Abi-Dargham A, Lieberman JA, Horga G*, Girgis RR*. Distinct Relationships Between Visual and Auditory Perceptual Abnormalities and Conversion to Psychosis in a Clinical High-Risk Population. JAMA Psychiatry. 2016 Nov 16. Download Publication (PDF)

Abi-Dargham A, Horga G. The search for imaging biomarkers in psychiatric disorders. Nat Med. 2016 Nov;22(11):1248-1255. Download Publication (PDF)

Alderson-Day B, Diederen K, Fernyhough C, Ford JM, Horga G, Margulies DS, McCarthy-Jones S, Northoff G, Shine JM, Turner J, van de Ven V, van Lutterveld R, Waters F, Jardri R. Auditory Hallucinations and the Brain's Resting-State Networks: Findings and Methodological Observations. Schizophr Bull. 2016 Sep;42(5):1110-23. Download Publication (PDF)

Horga G*, Cassidy CM, Xu X, Moore H, Slifstein M, Van Snellenberg JX, Abi-Dargham A. “Dopamine-related disruption of functional topography of striatal connections in unmedicated patients with schizophrenia,” JAMA Psychiatry. 2016 Aug 1;73(8):862-70. Download Publication (PDF)

Reinen JM, Van Snellenberg JX, Horga G, Abi-Dargham A, Daw ND, Shohamy D. Motivational Context Modulates Prediction Error Response in Schizophrenia. Schizophr Bull. 2016 Nov;42(6):1467-1475. Download Publication (PDF)

Cassidy CM, Van Snellenberg JX, Benavides C, Slifstein M, Wang Z, Moore H, Abi-Dargham A, Horga G*. "Dynamic connectivity between brain networks supports working memory: relationships to dopamine release and schizophrenia," J Neurosci. 2016 Apr 13;36(15):4377-88. Download Publication (PDF)

Van Snellenberg JX, Girgis RR, Horga G, van de Giessen E, Sliftein M, Ojeil N, Weinstein JJ, Moore H, Lieberman JA, Shohamy D, Smith EE, Abi-Dargham A. “Mechanisms of working memory impairment in schizophrenia,” Biol Psychiatry. 2016 Oct 15;80(8):617-26. Download Publication (PDF)

Colibazzi T, Horga G, Wang Z, Huo Y, Corcoran C, Klahr K, Brucato G, Girgis R, Gill K, Abi-Dargham A, Peterson BS. “Neural Dysfunction in Cognitive Control Circuits in Persons at Clinical High-Risk for Psychosis,” Neuropsychopharmacology. 2016 Apr;41(5):1241-50. Download Publication (PDF)

Horga G, Maia TV, Marsh R, Hao X, Xu D, Duan Y, Tau GZ, Graniello B, Wang Z, Kangarlu A, Martinez D, Packard MG, Peterson BS. “Changes in Corticostriatal Connectivity During Reinforcement Learning in Humans,” Hum Brain Mapp. 2015 Feb;36(2):793-803. Download Publication (PDF)

Horga G*, Schatz KC, Abi-Dagham A, Peterson BS. “Deficits in Predictive Coding Underlie Hallucinations in Schizophrenia,” J Neurosci. 2014 Jun 11;34(24):8072-82. Download Publication (PDF)

Horga G, Abi-Dargham A. “The Striatum and Dopamine: A Crossroad of Risk for Schizophrenia,” JAMA Psychiatry. 2014 May 12. Download Publication (PDF)

Horga G*, Fernandez-Egea E, Mane A, Font M, Schatz KC, Falcon C, Lomena F, Bernardo M, Parellada E. “Brain metabolism during hallucination-like auditory stimulation in schizophrenia,” PLoS One. 2014 Jan 8;9(1): e84987. Download Publication (PDF)

Peterson BS, Wang Z, Horga G, Warner V, Liu J, Graniello G, Rutherford B, Gerber A, Wickramaratne P, Garcia F, Wang P, Yu S, Hao X, Adams PB, Klahr KW, Qian M, Weissman MM. “Brain Activations Discriminate Risk and Resilience Endophenotypes From Markers of Lifetime Illness in Familial Major Depressive Disorder,” JAMA Psychiatry. 2014 Feb;71(2):136-48. Download Publication (PDF)

Marsh R, Horga G, Parashar N, Wang Z, Peterson BS, Simpson HB. “Altered Activation in Fronto-Striatal Circuits During Sequential Processing of Conflict in Unmedicated Adults with Obsessive-Compulsive Disorder,” Biol Psychiatry. 2013 Apr 15;75(8):615-22. Download Publication (PDF)

Horga G, Maia TV, Wang P, Wang Z, Marsh R, Peterson BS. “Adaptation to conflict via context-driven anticipatory signals in the dorsomedial prefrontal cortex,” J Neurosci. 2011 Nov 9;31(45):16208-16. Download Publication (PDF)

Horga G, Maia TV. Conscious and unconscious processes in cognitive control: a theoretical perspective and a novel empirical approach. Front Hum Neurosci. 2012 Jul 4;6:199. Download Publication (PDF)

Marsh R, Horga G, Wang Z, Wang PW, Klahr KW, Berner LA, Walsh BT, Peterson BS. “An fMRI study of self-regulatory control and conflict resolution in adolescents with Bulimia Nervosa,” Am J Psychiatry. 2011 Nov;168(11):1210-20. Download Publication (PDF)

Horga G, Bernacer J, Dusi N, Entis JJ, Kingwai Chu, Hazlett EA, Haznedar MM, Kemether E, Byne W, Buchsbaum MS. “Correlations between ventricular enlargement and gray and white matter volumes of cortex, thalamus, striatum and internal capsule in schizophrenia,” Eur Arch Psychiatry Clin Neurosci. 2011 Mar 24. Download Publication (PDF)

Horga G, Parellada E, Lomena F, Fernandez-Egea E, Mane A, Font M, Falcon C, Konova A, Pavia J, Ros D, Bernardo M. “Differential brain glucose metabolic patterns in antipsychotic-naive first episode schizophrenia with and without auditory verbal hallucinations,” J Psychiatry Neurosci. 2011 Jan 1;36(1):100085. Download Publication (PDF)