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“The effectiveness of combinations of antipsychotic medications remains unclear; reviews of this treatment strategy agree on the need for further investigation,” Dr. T. Scott Stroup and team wrote.

“Novel approaches for addressing pain and opioid use are critically needed,” writes Dr. Sandra D. Comer and colleagues.

"Many people with mental illness are susceptible to undue influence and impulsive actions, leaving them vulnerable to advocates for physician-assisted death," said Dr. Paul Appelbaum.