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“There was a lot of social isolation, a lot of loneliness," said Columbia's Dr. Mark Olfson. "And those are things that psychotherapy is designed to address, in a way that medication can't."

“If you get through the first two years of this experience and feel like you have a future and have a sense of personhood, and you can be somebody—what a difference,” said OnTrackNY's Dr. Lisa Dixon.

A Columbia study revealed that antidepressants that exclusively interact with intestinal cells could be far more effective in treating depression and anxiety and result in fewer digestive issues.

Columbia’s Jeffrey M. Cohen, PsyD, and colleagues offer strategies for healthcare providers to proactively discuss sexual orientation and gender identity with youths and their families.