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While 15 to 30% of people will have at least one panic attack in their life, only two to four percent will develop panic disorder, said Franklin Schneier, MD.

The question boils down to: Do antidepressants work? "I think they do,” Dr. David Hellerstein said.

There is evidence that the puzzles were specifically more effective for people in the "late" stage of mild cognitive impairment, Davangere Devanand, MD, said.