Conte Center for Suicide Prevention
Neuroscience Of Mental Disorders: The Neurobiology Of Suicidal Behavior
The Conte Center for Suicide Prevention is dedicated to the investigation of clinical and neurobiological correlates of suicidal behavior across the life cycle. The Center has successfully tested a predictive model for suicidal behavior in a prospective study and identified much detail about the role of the serotonin system in the diathesis for suicidal behavior. We have identified a role for certain genes in modulating environmental effects (life events and childhood adversity) on suicidal behavior. The current Center goals focus on studying brain circuits and molecular mechanisms of abnormal stress responses in suicide and nonfatal suicidal behavior.