The department has 17 Centers in total, five of which are NIH-funded (starred are federally funded). The function of Centers in the Department of Psychiatry is to foster research on a given disorder or population, utilizing any and all relevant expertise from the 12 Research Areas, and drawing on resources from any of the Clinical Divisions and Research Cores.

• Center of Excellence for Cultural Competence
• Center for Healing Opioid and Other Substance Use Disorders (CHOSEN)
• Center for Practice Innovations
• Center for Research on Ethical, Legal & Social Implications of Psychiatric, Neurologic & Behavioral Genetics (NHGRI)*
• Clinical Cognitive Computational Neuroscience Center (C3N)
• HIV Center for Clinical and Behavioral Studies*
• Kavli Institute for Brain Science
• Lieber Center for Schizophrenia Research and Treatment
• Lyme and Tick-Borne Diseases Research Center
• Medication Development Research Center at the Division on Substance Use Disorders
• Neuroscience Of Mental Disorders: The Neurobiology Of Suicidal Behavior (Conte Center)*
• ​Northeast/Caribbean AIDS Education and Training*
• OPAL Center*
• Psychoanalytic Center
• Reiner Center for Behavioral and Psychosomatic Medicine
• Sackler Center for Developmental Psychobiology
• Stroud Center for Aging Studies

* Federally funded