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“With some mental health conditions, in particular, psychotic disorders, I think there is a genetic or a biological component that can interact with a life stressor,” says Dr. Jeffrey Cohen.

Dr. Michael Grunebaum says that in his clinical trials, many patients don’t find that the drug relieves anxiety. “Ketamine is just a really distinct, weird, spacey feeling,” he says.

A discussion with Dr. Deborah Cabaniss and Dr. Yael Holoshitz about their new book Different Patients, Different Therapies: Optimizing Treatment Using Differential Psychotherapuetics.

Two people venting ad nauseam to one another about shared stressors is called “co-rumination,” and Dr. Sarah Frankel warns it can heighten anxiety.