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Clinicians evaluating adolescents and young adults who have engaged in self-harm should carefully assess them for a history of other forms of violence, noted Dr. Mark Olfson.

“It’s a drug that seems to act at a wide range of brain sites so in terms of anxiety, one of its potential mechanisms could be acting at one of the serotonin receptors," said Dr. Margaret Haney.

“If you increase the prevalence of users, you are going to increase the prevalence of people who have adverse consequences,” said lead author Dr. Deborah Hasin.