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“You don’t expect to see a sudden change in mental status,” said Dr. Jeremy Veenstra-VanderWeele, referring to people with autism. “When it happens, it means there’s something else going on.”

"OCD is characterized by the presence of obsessions, compulsions, or both," says Dr. Erin Engle. It's those intrusive thoughts that spur tell-tale OCD behaviors like repeated hand washing.

Lower diagnosis rates for Hispanic children and girls might be partly explained by cultural biases and not necessarily a lower risk of autism for these children, said Dr. Jeremy Veenstra-VanderWeele.

Dr. Jonathan Stewart, who is currently running a wake therapy trial, only keeps patients awake for one night. “I couldn’t see a lot of people agreeing to stay in hospital for three nights," he said.