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Jermaine Jones, PhD, a neuroscientist at Columbia, teaches people to rouse individuals experiencing a fentanyl overdose by giving them a firm rub with their knuckles in the center of the chest.

Chacku Mathai, a project director with OnTrackNY, thinks about whether, if the perfect antipsychotic existed, he would take it. “My experience is so rich,” he said, “I wouldn’t trade it for anything.”

"There's no way that these drugs can meet the fantasized expectations that people have,” David Hellerstein, MD, a professor of clinical psychiatry at Columbia, said in reference to psychedelics.