Current Studies

  • Principal Investigator

    J. John Mann, MD
    This research study uses brain imaging to explore the biological causes of depression andsuicidal behavior. Our ultimate goal is to improve prevention of suicide. Participation includesbrain imaging scans (MRI and PET), neuropsychological tasks and clinical assessment. Eligibleindividuals will be compensated up to $475. Although we have paused all research proceduresdue to the recommended COVID-19 safety regulations, we are continuing to screen by telephonefor eligibility. No in-person visits are required at this time. In-person screening and procedureswill resume after the pause is lifted.
  • Principal Investigator

    J. John Mann, MD
    This research study uses brain imaging to explore the biological causes of major depression andwhy some people feel suicidal or may act on such thoughts. Our ultimate goal is to improveprevention of suicide. Individuals may qualify if they have depression with or without suicidalthoughts or previous suicide attempts. Participation involves a detailed diagnostic set ofinterviews, brain imaging scans (MRI and PET) and neuropsychological tasks. Eligibleindividuals will be compensated up to $475 and may receive up to 6 months of free doctor visitsfor medication-based treatment.
  • Principal Investigator

    Francesca Zanderigo, PhD
    Note: Due to COVID-19, all the research procedures, except the phone screening for this study, has been on pause. The in-person screening and the research procedures will start after the pause is lifted. The purpose of this study is to examine the use of a new portable brain imaging device to study a measure of brain activity, and to develop optimal methods for analyzing the data from this device.
  • Principal Investigator

    Jeffrey M. Miller, MD
    The goal of this study is to examine how effective and well-tolerated a possible new treatment for individuals who injure themselves frequently will be. We are studying a minimal-risk form of electrical brain stimulation called transcranial direct current stimulation, or tDCS. Previous studies using tDCS have shown that it is helpful in treating conditions like depression and chronic pain. tDCS is administered using two small electrodes that are applied to the scalp. A low current is applied to the electrodes using a battery-operated device.
  • Principal Investigator

    Jeffrey M. Miller, MD
    The goal of this study is to examine how effective and well-tolerated a possible new treatment for individuals who injure themselves frequently will be. We are studying a minimal-risk form of electrical brain stimulation called transcranial direct current stimulation, or tDCS. Previous studies using tDCS have shown that it is helpful in treating conditions like depression and chronic pain. tDCS is administered using two small electrodes that are applied to the scalp. A low current is applied to the electrodes using a battery-operated device.
  • Principal Investigator

    Jeffrey M. Miller, MD
    The goal of this study is to examine how effective and well-tolerated a possible new treatment for individuals who injure themselves frequently will be. We are studying a minimal-risk form of electrical brain stimulation called transcranial direct current stimulation, or tDCS. Previous studies using tDCS have shown that it is helpful in treating conditions like depression and chronic pain. tDCS is administered using two small electrodes that are applied to the scalp. A low current is applied to the electrodes using a battery-operated device.
  • Principal Investigator

    Barbara H. Stanley, PhD
    This study conducts behavioral tasks to explore the biological causes of depression and suicidalbehavior. Our ultimate goal is to improve prevention of suicide. Participants will have depressionwith or without suicidal thoughts or previous suicide attempts. Participation involves clinicalassessments, a week-long phone survey, a stress test and computer games. Eligible individuals willbe compensated up to $125 and will receive up to 3 months of free doctor visits for medicationbased treatment.
  • Principal Investigator

    Barbara H. Stanley, PhD
    This research study conducts behavioral tasks to explore the biological causes of depression andsuicidal behavior. Our ultimate goal is to improve prevention of suicide. Participation in this studyincludes clinical assessments, a week-long phone survey, a stress test and a computer game.Eligible individuals will be compensated up to $125. Although we have paused all in-personresearch procedures due to the recommended COVID-19 safety regulations, we are continuing toscreen by telephone for eligibility. No in-person visits are required at this time.