Dr. Jeffrey Lieberman and co-authors hypothesized that combining the xanomeline with trospium could lessen xanomeline's typical side effects in treating schizophrenia.
The Horga Lab is a psychiatry research lab that uses neuroimaging and cognitive methods to study the origins of the psychotic symptoms of schizophrenia, including hallucinations and delusions.
“Our findings open the door for the development of treatments to target specific symptoms of psychosis depending on an individual subject’s symptom profile," says Guillermo Horga, MD, PhD