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“College aged youth are among the most vulnerable to the onset of many mental disorders — including anxiety, mood, eating, psychotic and substance-use disorders,” writes Dr. Jeffrey A. Lieberman.

Dr. Cristiane S. Duarte pointed out limitations in the study, such as cultural variation and scarcity of data in conflict-affected settings, that should be addressed in future research.

“As we treat more people with ketamine, an unfortunate side effect of that is more exposure, which means that we're going to create more ketamine addicts,” said Dr. Drew Ramsey.

“If we have a way of targeting the ambivalence — and the way you do that is long-acting preparation — that will be a major advance,” Dr. Adam Bisaga said.