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“The idea that marijuana could help curb the opioid epidemic, which has received a fair amount of media attention, struck me as clinically counterintuitive,” said study author Dr. Mark Olfson.

Anxiety is a signal telling you something is lurking that you're afraid of, says Dr. Franklin Schneier. To diminish it, "I try to pin down the fear to something as specific as possible," he says.

"It has long been known that people with depression tend to crave sweets," Dr. James Gangwisch says.

Those who smoked marijuana were almost six times more likely to develop misuse of prescription opioids and almost eight times more likely to develop an opioid use disorder, said Dr. Mark Olfson.