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There are major problems with patient adherence to prescribed medications for disorders like bipolar and schizophrenia, says Dr. Paul Appelbaum.

“Increased use would exacerbate the effects,” said Dr. Ziva Cooper. People who use synthetic cannibanoids - commonly known as Spice or K2 - show “a constellation of adverse effects,” Cooper said.

The problem of not adhering to treatment, is if medication is administered daily, or multiple times per day, is that it compromises its effectiveness, says Dr. Jeffrey Lieberman.