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Dr. Arthur Williams suggests shifting patients who use benzodiazepines away from full-strength opioids to painkillers with a much lower risk of respiratory suppression and overdose.

“What you see is the number of long-term users just piling up year after year,” said Dr. Mark Olfson.

“Based on our study and those of other researchers, we can say with some confidence that SSRI medications have an influence of fetal brain development,” said study coauthor Dr. Jiook Cha.

Initially, Seroquel seemed to have few side effects or complications. “The risks are far greater than I think has been represented,” said Dr. Mark Olfson.