Early Neuroimaging, Neuroimmune, and Neuropsychology (N³) Lab
Location and Contact Information
Principal Investigator
The overarching goal of Early Neuroimaging, Neuroimmune, and Neuropsychology Lab (Early N3 Lab) is to identify early immune, brain, and neuropsychological antecedents of childhood psychiatric risk to reduce the time to intervention for young children. This is accomplished through two complementary lines of study involving national and international birth cohorts, and clinical samples of pregnant women. Dr. Marisa Spann currently has a NIMH R01 to study the effects of maternal immune activation (infection and inflammation) on early brain and emotion regulation development in a Finnish national birth cohort and a newly recruited sample of pregnancy women at Columbia University Irving Medical Center. She also has another NIMH R01 to identify circuit-based markers of regulatory deficits that are passed inter-generationally and persist from infancy to early childhood.
Lab Members
Director
Research Manager
Sanjana Inala, MPH
Research Assistants
Kayla Delapenha, B.S.
Iqra Ali, B.A.
Victoria Mulligan, M.S.
Affiliate Researchers
Bin Cheng, PhD
- Professor of Biostatistics at the Columbia University Medical Center
Grace Liu, MS
- Senior Data Manager (Division of Behavioral Medicine) at the Columbia University Medical Center
Vinus Mahmoodi, PhD
- Assistant Professor of Clinical Psychology (in Psychiatry) at the Columbia University Medical Center
Vincenzo Lauriola, PhD
- Assistant Professor of Behavioral Medicine (in Psychiatry) at the Columbia University Medical Center
Xuejun Hao, PhD
- Assistant Professor of Clinical Neurobiology (in Psychiatry) at the Columbia University Medical Center
Alumni
Erica Lambeth, BA
Antonette Davids, BA
Kristiana Barbato, BA
Ezra Aydin, PhD
Isabelle Mueller, PhD
Ayanna Gilmore, MA
Manya Balachander, BS
Sanjana Murthy, BS
Shely Khaikin, BA
Cristin Holland, PhD
Rachel Ababio, BA
Select Publications
Spann MN, Bansal R, Hao, X, Rosen, TS, Peterson BS (2020). Prenatal socioeconomic status and social support are associated with neonatal brain morphology, toddler language and psychiatric symptoms(link is external and opens in a new window). Child Neuropsychology, 26(2):170-188. PMID: 31385559 PMCID: PMC6930975
Spann MN, Cheslack‐Postava K, Brown AS (2020). The association of serologically documented maternal thyroid conditions during pregnancy with bipolar disorder in offspring(link is external and opens in a new window). Bipolar Disorders, 22(6):621-628. PMID: 31758834
Scheinost D, Spann MN, McDonough L, Peterson BS, Monk C (2020). Associations between different dimensions of prenatal distress, neonatal hippocampal connectivity, and infant memory(link is external and opens in a new window). Neuropsychopharmacology, 45(8):1272–1279. PMID: 32305039 PMCID: PMC7297970