For further information about the causes, symptoms, and treatment of depression, please refer to the following books, pamphlets, and useful links to other web sites.

In the News

Chronobiology Comes of Age by Wirz-Ju

The Power of Wake: Can Depression be Treated Effectively Without Medication or Therapy by David Hellerestein, MD



Understanding Depression: A Complete Guide to Its Diagnosis and Treatment
Donald F. Klein, M.D. and Paul H. Wender, M.D. Oxford University Press, New York, 1993
A readable guide to the causes, course, and symptoms of depression that includes several self-rating tests.

The Antidepressant Sourcebook: A User’s Guide for Patients and Families
Andrew L. Morrison, M.D.
Doubleday, New York, 2005

With numerous case studies, this practical reference tool reviews the major types of antidepressant medications and the symptoms of clinical depression.


Depression (NIH Publication No. 04-3561)
Margaret Strock
National Institute of Mental Health, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD, 2000
This 20-page booklet describes symptoms, causes, and treatments of depression and offers tips on getting help and coping

Journal Articles

  • Agosti, V. (1999, July). One year clinical and psychosocial outcomes of early-onset chronic depression. Journal of Affective Disorder, 54(1-2), 171-175.
  • Agosti, V., Hellerstein, D. J., & Stewart, J. W. (2009, November/December). Does personality disorder decrease the likelihood of remission in early-onset chronic depression? Comprehensive Psychiatry, 50(6), 491-495.
  • Agosti, V., & Stewart, J. W. (2007, September). Efficacy and safety of antidepressant monotherapy in the treatment of bipolar-II depression. International Clinical Psychopharmacology, 22(5), 309-311.
  • Agosti, V., Quitkin, F. M., Stewart, J. W., & McGrath, P. J. (2002, November). Somatization as a predictor of medication discontinuation due to adverse events. International Clinical Psychopharmacology, 17(6), 311-314.
  • Bruder, G. E., Stewart, J. W., McGrath, P. J., Deliyannides, D., & Quitkin, F. M. (2004, September). Dichotic listening tests of functional brain asymmetry predict response to fluoxetine in depressed women and men. Neuropsychopharmacology, 29(9), 1752.
  • Donovan, S. J., Stewart, J. W., Nunes, E. V., Quitkin, F. M., Parides, M., Daniel, W., Klein, D. F. (2000, May). Divalproex treatment for youth with explosive temper and mood lability: A double-blind, placebo-controlled crossover design. American Journal of Psychiatry, 157, 818-820.
  • Deliyannides, D. A., Nunes, E. V., Quitkin, F. M., & Brady, R. (1996, January). Lithium treatment of aggressive behavior in depressed, drug-dependent patients. The American Journal on Addictions, 5(1), 87-90.
  • Hellerstein, D. J., Agosti, V., Bosi, M., & Black, S. R. (2010, December). Impairment in psychosocial functioning associated with dysthymic disorder in the NESARC study. Journal of Affective Disorders, 127(1-3), 84-88.
  • Hellerstein, D. J., Batchelder, S., Hyler, S., Arnaout, B., Corpuz, V., Coram, L., & Weiss, G. (2008, April). Aripiprazole as an adjunctive treatment for refractory unipolar depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 32(3), 744-750.
  • Hellerstein, D. J., Batchelder, S., Miozzo, R., Kreditor, D., Hyler, S., Gangure, D., & Clark, J. (2004, May). Citalopram in the treatment of dysthymic disorder. International Clinical Psychopharmacology, 19(3), 143-148.
  • Hellerstein, D. J., Kocsis, J. H., Chapman, D., Stewart, J. W., & Harrison, W. (2000, September). Double-blind comparison of sertaline, imipramine, and placebo in the treatment of dysthymia: Effects on personality. The American Journal of Psychiatry, 157(9), 1436-1444.
  • Hellerstein, D. J., Skodol, A. E., Petkova, E., Xie, H., Markowitz, J. C., Yen, S., Grilo, C. (2010, September/October). The impact of comorbid dysthymic disorder on outcome in personality disorder. Comprehensive Psychiatry, 51(5), 449-457.
  • Liebowitz, M. R., Quitkin, F. M., Stewart, J. W., McGrath, P. J., Harrison, W. M., Markowitz, J. S., & Rabkin, J. G. (1988, February). Antidepressant specificity in atypical depression. Arch Gen Psychiatry, 45(2), 129-137.
  • McElhiney, M. C., Rabkin, J. G., Gordon, P. H., Goetz, R., & Mitsumoto, H. (2009, October). Prevalence of fatigue and depression in ALS patients and change over time. Journal of Neurology, Neurosurgery & Psychiatry, 80(10), 1146-1149.
  • McElhiney, M., Rabkin, J., Van Gorp, W., & Rabkin, R. (2010, June). Modafinil effects on cognitive function in HIV+ patients treated for fatigue: A placebo controlled study. Journal of Clinical and Experimental Neuropsychology, 32(5), 474-480.
  • McGrath, P. J., Nunes, E. V., Stewart, J. W., Goldman, D., Agosti, V., Ocepek-Welikson, K., & Quitkin, F. M. (1996, March). Imipramine treatment of alcoholics with primary depression. Arch Gen Psychiatry, 53(3), 232-240.
  • McGrath, P. J., Stewart, J. W., Fava, M., Madhukar, T. H., Wisniewski, S. R., Nierenberg, A. A., Davis, L. (2006, September). Tranylcypromine versus venlafaxine plus mirtazapine following three failed antidepressant medication trials for depresson. American Journal of Psychiatry, 163, 1531-1541.
  • Nunes, E. V., Deliyannides, D. A., Donovan, S., & McGrath, P. J. (1996, June 1). The management of treatment resistance in depressed patients with substance use disorders. The Psychiatric Clinics of North America, 19(2), 311-327.
  • Nunes, E. V., Quitkin, F. M., Donovan, S. J., Deliyannides, D., Ocepek-Welikson, K., Koenig, T., McGrath, P. J.(1998). Imipramie treatment of opiate-dependent patients with depressive disorders. Arch Gen Psychiatry, 55(2), 153-160.
  • Rabkin, J. G., McElhiney, M. C., Moran, P., Acree, M., & Folkman, S. (2009, January). Depression, distress and positive mood in late-stage cancer: A longitudinal study. Psycho-Oncology, 18(1), 79-86.
  • Rabkin, J. G., McElhiney, M. C., Rabkin, R., & Ferrando, S. J. (2004, December). Modafinil treatment for fatigue in HIV+ patients: A pilot study. Journal of Clinical Psychiatry, 65(12), 1688-1695.
  • Rabkin, J. G., Wagner, G. J., McElhiney, M. C., Rabkin, R., & Lin, S. H. (2004, August). Testosterone versus fluoxetine for depression and fatigue in HIV/AIDS: A placebo-controlled trial. Journal of Clinical sychopharmacology, 24(4), 379-385.
  • Stewart, J. W., Deliyannides, D. A., & McGrath, P. J. (2008, November). Is duloxetine effective treatment for depression with atypical features? International Clinical Psychoparmacology, 23(6), 333-336.
  • Stewart, J. W., Bruder, G. E., McGrath, P. J., Quitkin, F. M. (2003, May). Do age of onset and course of illness define biologically distinct groups within atypical depression? Journal of Abnormal Psychology, 112(2), 253-262.
  • Stewart, J. W., McGrath, P. J., Quitkin, F. M., & Klein, D. F. (2007, February). Atypical depression: Current status and relevance to melancholia. Acta Psychiatrica Scandinavica, 115, 58-71.
  • Wagner, G., Rabkin, J., & Rabkin, R. (1997). Effects of testosterone replacement therapy on sexual interest, function and behavior in HIV+ men. Journal of Sex Research, 34(1), 27-33.
  • Wagner, G., Rabkin, J., & Rabkin, R. (1998, June). Exercise as a mediator of psychological and nutritional effects of testosterone therapy in HIV+ men. Medicine & Science in Sports & Exercise, 30(6), 811-817.

Useful Links

  • Depression Central
    A clearinghouse for information on all types of depressive disorders and their treatment.
  • Mood Disorders Support Group
    The web site for the Mood Disorders Support Group of New York City, a non-profit, self-help organization that serves individuals with depression and bipolar disorder and their families and friends. This site offers a comprehensive list of links regarding mood disorders.
  • National Alliance for the Mentally Ill (NAMI)
    The web site for the National Alliance for the Mentally Ill (NAMI), a non-profit, grassroots, self-help, support and advocacy organization of consumers, families, and friends of people with mental illnesses. This site offers many useful links to information on depressive disorders.
  • National Institute of Mental Health (NIMH)
    The lead Federal agency for research on mental and behavioral disorders offers information about the signs, symptoms, diagnosis, and treatment of depression and offers tips on how to locate mental health services in your area.
  • Obsessive-Compulsive Disorder Research Program, Anxiety Disorders Clinic, New York State Psychiatric Institute and Columbia University
    This web site is devoted to education about Obsessive Compulsive Disorder (OCD) and provides information on how to volunteer to participate in Obsessive Compulsive Disorder studies at the New York State Psychiatric Institute.
  • Social Anxiety Clinic, New York State Psychiatric Institute, and Columbia University
    This web site is devoted to education about Social Anxiety Disorder (SAD) and provides information on how to volunteer to participate in a Social Anxiety treatment study at the New York State Psychiatric Institute. Visitors can take an online Social Anxiety Self-Assessment that measures the severity of their social concerns.
  • Center for the Study of Trauma & Resilience, New York State Psychiatric Institute and Columbia University
    This web site offers information on our research program that includes specialized treatment for 9/11-related PTSD at no cost and an intensive resilience-building group program offered at September Space in Lower Manhattan. In addition, the web site is dedicated to education about Posttraumatic Stress Disorder (PTSD) and grief-related problems and describes other treatment and research efforts underway at the Center.