Grand Rounds Calendar

1. To describe the challenges in informed consent for treatment with psychedelics
2. To identify the unique boundary issues that arise in psychedelic treatment 
3. To anticipate the likely impact of commercialization of psychedelic treatment

1. Smith WR, Sisti D. Ethics and ego dissolution: the case of psilocybin. J Med Ethics. 2021;47:807-814.
2. Smith WR, Appelbaum PS. Novel ethical and policy issues in psychiatric uses of psychedelic substances. Neuropharmacology. 2022;216:109165.
3. Bradberry MM, Appelbaum PS, Gukasyan N. (2024). Informed Consent in Psychedelic-Assisted Therapy. In: Current Topics in Behavioral Neurosciences. Springer, Berlin, Heidelberg.

1. Learn how ACh is dysregulated in the brains of individuals with MDD.
2. Understand how preclinical models can be used to determine whether ACh contributes to the etiology of MDD in rodent models of stress-reactivity.
3. Identify brain areas in which ACh might contribute to stress-reactivity.

1. Mineur YS, Picciotto MR. The role of acetylcholine in negative encoding bias: Too much of a good thing? Eur J Neurosci. 2021 Jan;53(1):114-125. doi: 10.1111/ejn.14641. Epub 2019 Dec 24. PMID: 31821620; PMCID: PMC7282966.
2. Abdulla, Z.I., Mineur, Y.S., Crouse, R.B., Etherington, I.M., Yousuf, H., Na, J.J. and Picciotto, M.R. (2024) Acetylcholine signaling in the medial prefrontal cortex mediates the ability to learn an active avoidance response following learned helplessness training, Neuropsychopharmacology,(3):488-496. doi: 10.1038/s41386-024-02003-0. PMC11631976
3. Mineur, Y.S., Mose, T.N., Maibom, K.L., Pittenger, S.T. Soares, A.R. and Picciotto, M.R. (2022) Acetylcholine signaling modulates activity of the GABAergic signaling network in the basolateral amygdala and behavior in stress-relevant paradigms, Molecular Psychiatry, 27(12):4918-27 PMC10718266

1. Identify relevant lessons from the seminal works of Dr. Mary Cover Jones in clinical science and education
2. Identify contemporary models in popular culture to optimize CBT delivery and engagement
3. Identify opportunities for authentic, ecologically-minded community engagement and boundary spanning to implement meaningful CBT programs and interventions

1. Ginsburg, G. S., Becker-Haimes, E. M., Keeton, C., Kendall, P. C., Iyengar, S., Sakolsky, D., Albano, A. M., Peris, T., Compton, S. N., & Piacentini, J. (2018). Results from the Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS): Primary anxiety outcomes. Journal of the American Academy of Child & Adolescent Psychiatry, 57(7), 471–480. https://doi.org/10.1016/j.jaac.2018.03.018
2. Hoagwood, K. E., Purtle, J., Spandorfer, J., Peth-Pierce, R., & Horwitz, S. M. (2020). Aligning dissemination and implementation science with health policies to improve children’s mental health. American Psychologist, 75(8), 1130–1145. https://doi.org/10.1037/amp0000706
3. Metzger, I. W., Turner, E. A., Jernigan-Noesi, M. M., Fisher, S., Nguyen, J. K., shodiya-zeumault, s., & Griffith, B. (2023). Conceptualizing community mental health service utilization for BIPOC youth. Journal of Clinical Child and Adolescent Psychology, 52(3), 328–342. https://doi.org/10.1080/15374416.2023.2202236

1. Describe examples of disparities in mental health treatment of underserved youth
2. List multiple drivers of care disparities for Asian American youth
3. Identify evidence-based approaches for addressing the needs of Asian American youth at risk of health disparities, depression, or suicide

Disparities in Youth Suicide Prevention:

1. Yu, S.H.*, Kodish, T.*, Bear, L.+, O’Neill, J.C., Asarnow, J.R., Goldston, D., Cheng, K.K.*, Wang, X.*, Vargas, S.M*. & Lau, A.S. (2023). Leader and provider perspectives on implementing Safe Alternatives for Teens and Youth – Acute (SAFETY-A) in public school districts serving racial/ethnic minoritized youth. School Mental Health, 15, 583-599. https://doi.org/10.1007/s12310-023-09572-3
2. Chen, B.C.*, Lui, J.H.L.*, Benson, L.A. +, Lin, Y.R. +, Ponce, N., Innes-Gomberg, D. & Lau, A.S. (2022) After the Crisis: Racial/Ethnic Disparities and Predictors of Care Use Following Youth Psychiatric Emergencies. Journal of Clinical Child and Adolescent Psychology, 52, 360-375. https://doi.org/10.1080/15374416.2022.2127103
3. Kodish, T.*, Kim, J.J.*, Le, K.*, Yu, S.H*, Bear, L.+ & Lau, A.S. (2020). Multiple stakeholder perspectives on school-based responses to suicide risk in a diverse public school district.  School Mental Health, 12, 336–352. DOI: https://doi.org/10.1007/s12310-019-09354-w  
4. Kim, J.J.*, Kodish, T.*, Bear, L.+, El-Hendi, T.+, Duong, J.*, & Lau, A.S. (2018). Disparities in Follow-up Care for Asian American Youth Assessed for Suicide Risk in Schools.  Asian American Journal of Psychology, 9, 308-317.

School-Based Preventive Interventions Informed by Translational Research:

1. Doan, S., Yu, S.*, Wright, B.*, Fung, J., Saleem, F., & Lau, A.S. (2022).  Resilience and Family Socialization Processes in Ethnic Minority Youth: Illuminating the Achievement-Health Paradox. Clinical Child and Family Psychology Review 25, 75–92.  https://doi.org/10.1007/s10567-022-00389-1 
2. Lau, A.S., Kim, J.J.,* Nguyen, D.J.,* Nguyen, H.T*., Kodish, T.,* & Weiss, B. (2020). Effects of Preference on Outcomes of Preventive Interventions Among Ethnically Diverse Adolescents At-Risk of Depression.  Journal of Clinical Child and Adolescent Psychology. 49, 820-836. https://doi.org/10.1080/15374416.2019.1639514
3. Fung, J., Kim, J. J., Jin, J., Chen, G., Bear, L., & Lau, A. S. (2019). A Randomized Trial Evaluating School-Based Mindfulness Intervention for Ethnic Minority Youth: Exploring Mediators and Moderators of Intervention Effects. Journal of abnormal child psychology, 47(1), 1–19. https://doi.org/10.1007/s10802-018-0425-7