Current Studies

Here is a list of some of our current studies. For additional studies, please visit RecruitMe.

  • Principal Investigator:

    J. John Mann, MD
    This NIH-funded research study uses brain imaging to explore the biological causes of major depression and suicide. We hope to develop a better understanding of how people who feel depressed and suicidal cope with their feelings so we can improve treatment and prevention. You may qualify if you have depression with or without suicidal thoughts or previous suicide attempts. Participation involves a set of diagnostic interviews, brain imaging scans (MRI and PET) and neuropsychological tasks. Eligible individuals will be compensated up to $750 and may receive up to 3 months of free doctor visits...
  • Principal Investigator:

    J. John Mann, MD
    This research study uses brain imaging to explore the biological causes of major depression and why it sometimes causes suicidal thinking. We hope to improve treatment and prevention. You may qualify if you have depression with or without suicidal thoughts or suicide attempts. Participation involves detailed interviews, blood and hair sampling, brain imaging scans and a stress test (measuring the bodys response to stress during brief arithmetic and speech tasks). Eligible individuals will be compensated up to $1,350. We seek to minimize COVID-19 risk, by doing clinical assessments via...
  • Principal Investigator:

    Ragy R Girgis, MD
    Healthy volunteers, age 14-30 years, needed for research study to understand thoughts and feelings young people experience over time. Study requirements: 2-3 hours of interview over the course of 1-2 visits at the Columbia University Medical Center (CUMC)/New York State Psychiatric Institute (NYSPI). These visits can also be done remotely or over video. As a participant you will receive: $50 as well as reimbursement for local transportation to research appointments If you are eligible, you will offered to participate in any of a number of research studies. Volunteers under the age of 18 must...
  • Principal Investigator:

    Ragy R Girgis, MD
    Have you ever had unusual thoughts, experiences or feelings, or do you have a family member with schizophrenia or psychosis? If so, you may be eligible for our clinic and research program. Researchers at the New York State Psychiatric Institute are interested in how these experiences may change over time. Study requirements: 2-3 hours of interview over the course of 1-2 visits at the Columbia University Medical Center (CUMC)/New York State Psychiatric Institute (NYSPI). These visits can also be done remotely or over video. As a participant you will receive: $50 as well as reimbursement for...
  • Principal Investigator:

    Ragy R Girgis, MD
    Have you ever had unusual thoughts, experiences or feelings, or do you have a family member with schizophrenia or psychosis? If so, you may be eligible for our clinic and research program. Researchers at the New York State Psychiatric Institute are interested in how these experiences may change over time. Study requirements: 2-3 hours of interview over the course of 1-2 visits at the Columbia University Medical Center (CUMC)/New York State Psychiatric Institute (NYSPI). These visits can also be done remotely or over video. As a participant you will receive: $50 as well as reimbursement for...
  • Principal Investigator:

    Amy M. Rapp, PhD
    The goal of the project is to identify differences in learning in obsessive-compulsive disorder (OCD) by measuring the activity of the brain while participants complete computer tasks. Eligible participants will be asked questions about their medical and psychiatric history and perform tasks on a computer while an electroencephalogram (EEG) is recorded. While most study procedures will be conducted online or via videoconferencing, this study requires two in-person visits occurring eight weeks apart. During those eight weeks, participants with OCD will receive exposure and response prevention...
  • Principal Investigator:

    Elias Dakwar, MD
    This 12-week free and confidential outpatient research study is recruiting healthy adults who are currently seeking treatment for alcohol use. Participants will engage in twice-weekly clinic visits during which they will meet with a physician and complete measures with research assistants. Participants will also receive innovative, investigative medications twice throughout this trial (Weeks2 and 5) to help facilitate their engagement in treatment. Upon completion of the study, participants will be referred to appropriate community providers to ensure that they have the necessary means to...
  • Principal Investigator:

    Elias Dakwar, MD
    This 12-week free and confidential outpatient study is recruiting healthy adults who are currently seeking treatment for cocaine use. Participants will engage in twice-weekly clinic visits during which they will have mindfulness-based therapy sessions, meet with a physician, and complete measures with research assistants. Participants will also receive innovative investigational medications twice throughout this trial (Weeks 1 and 5) to help facilitate their engagement in treatment. Upon completion of the study, participants will be referred to appropriate community providers to ensure that...
  • Principal Investigator:

    Elias Dakwar, MD
    This free and confidential study is recruiting healthy adults who are currently seeking treatment for opioid use (heroin, painkillers). Participants will be admitted into our inpatient unit for the first 3 to 5 days of the study. In addition to traditional medications used during detoxification, you will also receive innovative, investigative medications that may help with the transition onto Vivitrol (extended-release nalrexone). After discharge from the inpatient unit, participants will engage in twice-weekly outpatient visits for 12 weeks. These visits involve therapy sessions, meeting...
  • Principal Investigator:

    Martin Picard, PhD
    This study examines normal individual differences in the ways that the body and the brain respond to emotions, and the role of mitochondria in the mind-body connection. Mitochondria are small parts of each cell that make energy to keep us alive. Participants will be asked to come for a single two full-day visit, including two nights at a hotel next to the research center (Columbia University Medical Center). The study visit will include a blood draw, a medical exam, a cognitive testing session, questionnaires, an MRI scan, and at-home collection of saliva and stool samples the following week...

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