Myrna Weissman, PhD

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Overview

Academic Appointments

  • Diane Goldman Kemper Family Professor of Epidemiology (in Psychiatry)

Dr. Weissman is a Professor of Epidemiology and Psychiatry, College of Physicians and Surgeons and the School of Public Health at Columbia University and Chief of the Department in Clinical-Genetic Epidemiology at New York State Psychiatric institute. Until 1987, she was a Professor of Psychiatry and Epidemiology at Yale University School of Medicine and Director of the Depression Research Unit. She was a Visiting Senior Scholar (1979-1980) at the Institute of Medicine, National Academy of Sciences, Washington, D.C. In 1974, she received a Ph.D. in chronic disease epidemiology from Yale University. Her current research is on epidemiology, detection, treatment; and the genetics of affective and anxiety disorders. 

Dr. Weissman has been a consultant to many private and public agencies, including the World Health Organization, the White House Office of Science and Technology Policy, the John D. and Catherine T. MacArthur Foundation, and the Institute of Medicine, National Academy of Science. She has been the author or a co-author of over 550 scientific articles and chapters, and 11 books, including Interpersonal Psychotherapy of Depression, Basic Books, New York, 1984, with her late husband, Gerald L. Klerman, Bruce J. Rounsaville, and Eve S. Chevron; A Comprehensive Guide to Interpersonal Psychotherapy, Basic Books, New York, 2000 with Gerald L. Klerman and John Markowitz; and Treatment of Depression: Bridging the 21st Century, API Press, 2001 and Weissman, a Clinician's Quick Guide to Interpersonal Psychotherapy, Oxford University Press, New York, NY: 2007.

Research

The Genetics of Epidemiology and Treatment of Mood and Anxiety Disorder

1) A 3-generation longitudinal study of families at high- and low-risk for depression, including MRI and genetic studies. 2) A genetic study of early onset recurrent depression. 3) A study examining the efforts of parental remission from depression on offspring psychopathology. 4) Studies of psychiatric disorders in primary care and efforts to provide evidenced-based economic treatment.

Research Interests

  • The genetics of major depression or panic disorder, studies of families at high risk for depression and other disorders. The study of the treatment of depressed parents and the effect of remission on their children. Interpersonal Psychotherapy.

Grants

BREAKING THE CYCLE OF INTERGENERATIONAL DISADVANTAGE: NEURODEVELOPMENT AMONG PUERTO RICAN CHILDREN (Federal Gov)

Sep 21 2016 - Aug 31 2023

THREE GENERATIONS AT HIGH AND LOW RISK FOR DEPRESSION FOLLOWED LONGITUDINALLY (Federal Gov)

Apr 24 2017 - Mar 31 2021

UNDERSTANDING THE ROLE OF BELIEF IN THE RESILIENCE OF FAMILIES AT RISK FOR DEPRESSION: RELIGION, BRAIN STRUCTURE AND FUNCTION (Private)

Jan 1 2015 - Dec 30 2017

CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION (Federal Gov)

Jul 1 2010 - Jan 31 2017

BIOSIGNATURES OF TREATMENT REMISSION IN MAJOR DEPRESSION (Federal Gov)

Sep 30 2010 - Jun 30 2016

CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION (Federal Gov)

Jul 1 2010 - May 31 2016

SERATONERGIC MODULATION OF BRAIN DEVELOPMENT: GENETIC AND PHARMACOLOGIC INFLUENCES ON STRUCTURE, FUNCTION, AND BEHAVIOR (Federal Gov)

Sep 1 2010 - Apr 30 2016

CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION (Federal Gov)

Jul 1 2010 - Jan 31 2016

SERATONERGIC MODULATION OF BRAIN DEVELOPMENT: GENETIC AND PHARMACOLOGIC INFLUENCES ON STRUCTURE, FUNCTION, AND BEHAVIOR (Federal Gov)

Sep 1 2010 - May 31 2015

CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION (Federal Gov)

Jul 1 2010 - Apr 30 2015

UNDERSTANDING THE ROLE OF BELIEF IN THE RESILIENCE OF FAMILIES AT RISK FOR DEPRESSION: RELIGION, BRAIN STRUCTURE & GENETICS (Private)

Jan 1 2010 - Nov 15 2014

PILOT STUDY OF GROUP INTERPERSONAL THERAPY AMONG DEPRESSED AFRICAN-AMERICAN (Private)

Jul 15 2011 - Jul 14 2014

PARENTAL REMISSION FROM DEPRESSION AND CHILD PSYCHOPATHOLOGY (Federal Gov)

Jul 1 2007 - Jun 30 2014

PRENATAL FACTORS AND RISK OF SCHIZOPHRENIA IN A FINNISH NATIONAL BIRTH COHORT (Federal Gov)

Jul 1 2013 - Apr 30 2014

CHILDREN AT HIGH AND AT LOW RISK FOR DEPRESSION (Federal Gov)

Jul 1 2010 - Jan 31 2014

IDENTIFYING GENETIC MODIFIERS OF THE SEROTONIN TRANSPORTER 5-HTTLPR IN MAJOR DEPRESSIVE DISORDER THROUGHT LINKAGE ANALY (Private)

Jul 15 2011 - Jul 14 2013

GENETIC ANALYSIS: PSYCHIATRIC AND OTHER COMPLEX DISEASES (Federal Gov)

Jul 15 2002 - Feb 28 2013

SERATONERGIC MODULATION OF BRAIN DEVELOPMENT: GENETIC AND PHARMACOLOGIC INFLUENCES ON STRUCTURE, FUNCTION, AND BEHAVIOR (Federal Gov)

May 1 2012 - May 2 2012

THE GENETICS OF PANIC DISORDER AND SOCIAL ANXIETY DISORDER: A PILOT MRI STUDY (Private)

Jul 1 2007 - Jun 30 2011

Selected Publications

  • Weissman MM, Pilowsky DJ, Wickramaratne P, Talati A, Wisniewski SR, Fava M, Hughes CW, Garber J, Malloy E, King C, Cerda G, Sood B, Alpert JE, Trivedi MH, Rush J. : Remission of Maternal Depression is Associated with Reductions in Psychopathology in their Children: A Star*D-Child Report.. JAMA 2006;295 (12): 1389-1398
  • Weissman MM, Wickramartne P, NomuraY, WarnerV, Pilowsky D, Verdeli H.: Offspring of depressed parents: 20 years later.. Am J Psychiatry 2006;163: 1001-1008
  • Weissman MM, Markowitz JC, Klerman GL.: A Clinician’s Quick Guide to Interpersonal Psychotherapy., Oxford University Press, New York, NY, USA, 2007
  • Peterson BS, Warber V, Bansal R, Zhu H, Hao X, Liu J, Durkin K, Adams PB, Wickramaratne P, Weissman MM. : Cortical Thinning in Persons at Increased Familial Risk for Major Depression.. Proc Nat Acad Sciences (PNAS) 2009;106(15): 6273-6278
  • Weissman MM, Wickramaratne, P, Pilowsky DJ, Poh E, Batten LA, Hernandez M, Flament MF, Stewart JA, McGrath P, Blier P, Stewart JW.: Treatment of Maternal Depression in a Medication Clinical Trial and Its Effect on Children. . American Journal of Psychiatry 2015;172(5): 450-459