Jeffrey M. Miller, MD

Board Certifications: 
Psychiatry
Accepting New Patients
Profile Headshot

Overview

Academic Appointments

  • Associate Professor of Clinical Psychiatry

Dr. Miller completed his residency in psychiatry as well as post-doctoral research training at Columbia University and The New York State Psychiatric Institute, where he is now Director of Brain Imaging in the Division of Molecular Imaging and Neuropathology, and Assistant Professor of Clinical Psychiatry.

His clinical and research interests focus on mood disorders, with goals of increasing our understanding of the neurobiology of mood disorders, predicting treatment outcome with medication and psychotherapeutic interventions, and developing more effective treatments, using functional brain imaging approaches.

Dr. Miller's research has been funded by NARSAD, the CTSA, The Paul Janssen Fellowship in Translational Neuroscience Research, and The National Institutes of Health.

Hospital Affiliations

  • NewYork-Presbyterian/Columbia

Gender

  • Male

Schedule an Appointment

Phone Appointments

New and Existing Patients:
646-774-7613

Location(s)

CUMC/Herbert Pardes Building of the New York State Psychiatric Institute
1051 Riverside Drive
New York, NY 10032
Primary

Credentials & Experience

Education & Training

  • Yale University School of Medicine, New Haven, CT
  • Residency: New York State Psychiatric Institute
  • Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center

Board Certifications

  • Psychiatry

Research

Dr. Miller uses brain imaging techniques including PET and fMRI to study the neurobiology of depression, and to identify predictors of treatment outcome with standardized treatments, including cognitive behavioral therapy.

His primary research interest involves using brain imaging techniques including neuroreceptor quantification via PET as well as fMRI to predict treatment outcome with standardized treatments for major depressive disorder.

The long-term goal of this work is to develop biomarkers that would allow clinicians to select treatments for patients suffering from depression based on the likelihood of response in individual patients

Research Interests

  • Depression, including treatment-refractory depression
  • Cognitive Behavioral Therapy

Grants

ANTECEDENTS OF SUICIDAL BEHAVIOR RELATED NEUROBIOLOGY (Federal Gov)

Jul 1 2018 - Jun 30 2019

NONINVASIVE QUANTIFICATION OF BRAIN GLUCOSE METABOLISM USING A PORTABLE POSITRON EMISSION TOMOGRAPHY CAMERA. (Federal Gov)

Jul 15 2018 - Mar 31 2019

ANTECEDENTS OF SUICIDAL BEHAVIOR RELATED NEUROBIOLOGY (Federal Gov)

Jul 1 2016 - Jun 30 2017

2/2 FAMILIAL EARLY-ONSET SUICIDE ATTEMPT BIOMARKERS (Federal Gov)

Aug 18 2015 - Apr 30 2016

DEFICITS OF THE 5-HT1A RECEPTORS SYSTEM AS A TRAIT MAKER IN MAJOR DEPRESSIVE DISORDER (Private)

Jul 1 2005 - Jun 30 2015

NOVEL MECHANISMS UNDERLYING DEPRESSION: PET IMAGING OF THE KAPPA OPIOID (Federal Gov)

Aug 16 2011 - Oct 31 2014

PREDICTING REMISSION FROM MAJOR DEPRESSION: COMBINING FUNCTI ONAL MRI AND POSITRON EMISSION TOMOGRAPHY (Private)

Jul 1 2007 - Jun 30 2010

RESEARCH TRAINING--AFFECTIVE AND RELATED DISORDERS (Federal Gov)

Jul 1 1978 - Jun 30 2009

Selected Publications

  • Miller JM, Brennan KG, Ogden RT, Oquendo MA, Sullivan GM, Mann JJ, Parsey RV: Elevated Serotonin 1A Binding in Remitted Major Depressive Disorder: Evidence for a Trait Biological Abnormality. Neuropsychopharmacology 2009;34: 2275-84
  • Miller JM, Oquendo MA, Ogden RT, Mann JJ, Parsey RV: Serotonin Transporter Binding as a Possible Predictor of One-Year Remission in Major Depressive Disorder. Journal of Psychiatric Research 2008;42: 1137-1144
  • McGrath PJ, Miller JM: Pharmacologic Management for Treatment-Resistant Unipolar Depression. Psychiatry, third edition, Tasman A, Kay J, Lieberman J, et al. (eds). 2008;2: 2372-2389
  • Miller JM, Vorel SR, Tranguch AJ, Kenny ET, Mazzoni P, van Gorp WG, Kleber HD: Anhedonia after a selective bilateral lesion of the globus pallidus. American Journal of Psychiatry 2006;163: 786-8
  • Miller JM, Kinnally EL, Ogden RT, Oquendo MA, Mann JJ, Parsey RV: Reported childhood abuse is associated with low serotonin transporter binding in vivo in major depressive disorder. Synapse 2009;67: 565-573