Davangere P. Devanand, MBBS, MD
Areas of Expertise / Conditions Treated
- Professor of Psychiatry (in Neurology and in the Gertrude H. Sergievsky Center) at CUMC
- Director of Geriatric Psychiatry
Dr. D. P. Devanand is Professor of Psychiatry and Neurology at the Columbia University Medical Center. He completed medical school at Christian Medical College, Vellore, in India, and trained in psychiatry at the National Institute of Mental Health and Neurosciences, Bangalore, India.
He completed psychiatry residency training at S.U.N.Y. Upstate Medical Center, Syracuse, NY, and Yale University School of Medicine in New Haven, CT. He then did a clinical research fellowship in Biological Psychiatry at Columbia University, and has continued on the faculty at Columbia University since 1987. Currently, he is Director of the DIvision of Geriatric Psychiatry, Co-Director of the Memory Disorders Center, and Co-Director of the Adult and Late Life Depression Clinic at the New York State Psychiatric Institute. His research studies involve Alzheimer’s disease and geriatric depression.
His research helped to define the clinical features and treatment response in elderly patients with dysthymic disorder, a chronic depressive illness. He pioneered studies on the interface between depression and cognitive impairment in the elderly, and is well-known for his research into early diagnostic markers of Alzheimer’s disease and the treatment of psychosis and agitation in this disorder. He has published research articles in major journals including a landmark study on antipsychotic discontinuation in Alzheimer’s disease in the New England Journal of Medicine, and articles in several journals including JAMA, Annals of Neurology, Neurology, Archives of General Psychiatry, and American Journal of Psychiatry. He has been principal investigator on several research grants from the National Institute of Aging and the National Institute of Mental Health. He has also been funded by the Department of Defense, Alzheimer’s Association, NARSAD, and the Dana Foundation.
He has received the International Psychogeriatric Association Research Award, the American Association of Geriatric Psychiatry Distinguished Investigator Award, and the American Psychiatric Association Jack Weinberg Memorial Award in geriatric psychiatry. He has published over 275 research papers and articles, and is the author of three books.
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Credentials & Experience
Education & Training
- State University of New York
- Residency: Yale University Hospital
- Residency: State University of New York - Downstate Medical Center
- Geriatric Psychiatry
Honors & Awards
2001 Distinguished Scientist Award, Indo-American Psychiatric Association
2003-present: listed in Best Doctors in America, Best Doctors in New York
2014 American Psychiatric Association Jack Weinberg Memorial Award in Geriatric Psychiatry
2015 American Association of Geriatric Psychiatry Distinguished Investigator Award
Research interests include treatment strategies for mild cognitive impairment and Alzheimer's disease, including treatment of psychosis and agitation in these disorders. Other interests include early diagnostic markers of Alzheimer's disease, and the interface between depression and cognitive impairment.
Anti-viral therapy in Alzheimer’s disease PI: Dr. Davangere Devanand, MD
Anti-viral therapy in Alzheimer’s disease is investigating the efficacy of treating patients with mild Alzheimer’s disease (AD) with the U.S.A marketed generic antiviral drug valacyclovir. Valacyclovir at 2g to 4g daily, repurposed as an anti-AD drug, is being compared to matching placebo in the treatment of 130 mild AD patients (65 valacyclovir, 65 placebo) who test positive for herpes simplex virus-1 (HSV1) or herpes simplex virus-2 (HSV2). The study is a randomized, double-blind, 18-month Phase II proof of concept trial. This study is funded by the NIH.
For more information, please contact Julianna Pollina at 646-774-8638.
Cognitive Training in Mild Cognitive Impairment PI: Dr. Davangere Devanand, MD
The purpose of this study is to evaluate if systematic cognitive training can improve cognitive performance in participants (ages 55-95 years) with memory loss. This study is evaluating the effects of Computerized Cognitive Training (CCT) for improvement in everyday cognitive and function status, in addition to long-term changes in brain networks over an 18- month period. Although there is no distribution of medication for this study, participants are required to have an at-home computer. This study is funded by the NIH.
For more information, please contact Jessica D’Antonio at 646-774-8674.
Treatment of Psychosis and Agitation in Alzheimer’s disease PI: Dr. Davangere Devanand, MD
This study involves a 12-week double-blind treatment trial in which adult outpatients with Alzheimer’s disease (AD) who have agitation/aggression with or without psychosis (hallucinations or delusions) will receive either low-dose lithium or placebo. Participants are allowed to receive other specific psychiatric medications if needed during the study, and will be closely monitored by physicians who specialize in memory disorders. Participants will receive open treatment with lithium, if clinically indicated, after completing the 12-week double blind trial. This study is funded by the NIH.
For more information, please contact Laura Simon-Pearson at 646-774-8671.
Escitalopram for Agitation in Alzheimer’s disease PI: Dr. Davangere Devanand, MD
This study involves a 12-week double-blind treatment trial in which adult outpatients with Alzheimer's disease (AD) who have agitation/aggression may receive escitalopram or placebo in combination with a psychosocial intervention. Participants will be closely monitored by physicians who specialize in memory disorders. After completing the 12-week double blind trial, participants will receive open treatment with Escitalopram for 12 weeks, if clinically indicated. This study is funded by the NIH.
For more information, please contact Laura Simon-Pearson at 646-774-8671.
- Neuropsychiatry/Cognitive Disorders
- Alzheimerâ€™s disease and age-related cognitive decline
“Treatment of Psychosis and Agitation in Alzheimer’s disease”: 5/15/2014-1/31/2020.
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