Ardesheer Talati, PhD

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Overview

Academic Appointments

  • Assistant Professor of Clinical Neurobiology (in Psychiatry)

Administrative Titles

  • Investigator, Sackler Institute for Developmental Psychobiology
  • Research Scientist, New York State Psychiatric Institute

Dr. Talati is Associate Professor of Clinical Neurobiology in Psychiatry at Columbia University Medical Center and New York State Psychiatric Institute. Both a neuroscientist and psychiatric epidemiologist by training, his interests lie in following long term neurobiological, behavioral, and clinical consequences of gestational (pregnancy) exposures to maternal illness, medication and substance use.

Dr. Talati is currently principal investigator of two multicenter R01s from the National Institute of Mental Health (NIMH) that address long-term effect on brain and behavioral development among offspring who were exposed to maternal depression or antidepressant medications during pregnancy. These multisite studies include populations in the United States, Canada, and Denmark and when completed, will examine offspring outcomes from birth through early adulthood.

In addition to the above, Dr. Talati has been funded by the National Institute on Drug Abuse (NIDA), the Brain and Behavior Research Foundation, and American Foundation for Suicide Prevention. He has served on review committees for the National Institute of Health as well as for Netherlands and United Kingdom funding agencies. He has received awards from the American College for Neuropsychopharmacology and the Organization for Human Brain Mapping.

Credentials & Experience

Education & Training

  • Fellowship in Clinical & Genetic Epidemiology, Columbia College of Physicians & Surgeons
  • PhD, Pharmacology & Neuroscience, Cornell University Medical College, NY

Research

Research Interests

  • Prenatal Epidemiology
  • Neurodevelopment
  • Birth Cohorts

Grants

NIMH R01MH114967

A multicohort assessment of gestational SSRI exposure on psychiatric outcomes

NIMH R01MH119510

Effects of prenatal maternal depression and antidepressant exposures on offspring neurodevelopmental trajectories: A birth cohort study

American Foundation for Suicide Prevention Independent Investigator Award

Identifying biomarkers in offspring at high risk for suicide

UNDERSTANDING THE ROLE OF BELIEF IN THE RESILIENCE OF FAMILIES AT RISK FOR DEPRESSION: RELIGION, BRAIN STRUCTURE AND FUNCTION (Private)

Jan 1 2015 - Dec 30 2017

EFFECTS OF PRENATAL SMOKE EXPOSURE ON OFFSPRING BRAIN AND BEHAVIOR. (Private)

Jan 15 2013 - Jan 14 2015

UNDERSTANDING THE ROLE OF BELIEF IN THE RESILIENCE OF FAMILIES AT RISK FOR DEPRESSION: RELIGION, BRAIN STRUCTURE & GENETICS (Private)

Jan 1 2010 - Nov 15 2014

THE GENETICS OF PANIC DISORDER AND SOCIAL ANXIETY DISORDER: A PILOT MRI STUDY (Private)

Jul 1 2007 - Jun 30 2011

Selected Publications

  • Talati, A., Keyes, K.M., Hasin, D.S.¬†Changing relationships between smoking and psychiatric disorders across twentieth century birth cohorts: clinical and research implications. Mol Psychiatry (Immediate Communication). 2016; 21(4):464-71 ¬† (http://www.ncbi.nlm.nih.gov/pubmed/26809837)
  • Talati, A, Bao, Y., Kaufman, J., Shen, L, Schaefer, C., Brown, A.S.: Maternal Smoking during Pregnancy and Bipolar Disorder in Offspring. American Journal of Psychiatry 2013;170(10):1178-85. ¬†( http://www.ncbi.nlm.nih.gov/pubmed/24084820)
  • Talati, A., Pantazatos, S.P., Schneier, F., Weissman, M.M., Hirsch, J. : Grey Matter Volume Abnormalities in Social Anxiety Disorder: A Primary, Replication, and Specificity Study. (2013). Biological Psychiatry 2013;73 (1): 75-84 (http://www.ncbi.nlm.nih.gov/pubmed/22748614)
  • Weissman, M.M., Brown, A.S., Talati, A.: Translational Epidemiology in Psychiatry: Linking Population to Clinical and Basic Sciences . Archives of General Psychiatry (JAMA Psychiatry) 2011;68: 660-668 (http://www.ncbi.nlm.nih.gov/pubmed/21646577)
  • Talati A, Ponniah K, Strug L, Hodge S, Fyer AJ, Weissman MM : Panic disorder, Social Anxiety Disorder, and a possible medical syndrome previously linked to Chromosome 13. Biological Psychiatry, 2008; 63(6): 594-601. (http://www.ncbi.nlm.nih.gov/pubmed/17920564)
  • BOOK CHAPTER:
  • Talati A, Weissman MM: Panic Disorder (in "Psychiatric Genetics"), Cambridge University Press, New York, NY, USA, 2012