Current Studies

Here is a list of some of our current studies. For additional studies, please visit RecruitMe.

  • The purpose of this study is to examine the use of a new portable brain imaging device to study a measure of brain activity, and to develop optimal methods for analyzing the data from this device. After baseline assessments including clinical interview, physical exam, and blood tests, participants will undergo 3 brain scans on separate days: two Positron Emission Tomography (PET) scans, each lasting one hour, using different PET cameras, to measure metabolic activity in the brain, and one Magnetic Resonance Imaging (MRI) scan, to obtain information about brain structure.
  • This study conducts behavioral tasks to explore the biological causes of depression and suicidal behavior. We hope to develop a better understanding of how people who feel depressed and suicidal cope with their feelings so we can improve treatment and prevention. Participants can have depression with or without a suicidal thoughts or any history of suicide attempts. Participation involves clinical assessments, a week-long phone survey, a stress test and computer games.
  • This study conducts behavioral tasks to explore the biological causes of depression and suicidal behavior. We hope to develop a better understanding of how people who attempt suicide differ from those who do not in order to improve prevention. Participation includes clinical assessments,a week-long phone survey, a stress test and a computer game. Eligible individuals will be compensated up to $125.
  • We are seeking individuals without any history of psychiatric disorders to serve as controls in our studies of OCD and anxiety. Studies may involve diagnostic interviews, MRI scans, and computer tasks. Compensation provided for time and travel.
  • This study uses smartphone technology to better understand changes in adolescent moods over time. As a participant in our study, we would: (a) interview your child about current and past thoughts, feelings, and behaviors and (b) collect data from your child's smartphone for 6 months through an app called the Effortless Assessment of Risk States (EARS; which would be installed during the initial study visit after you learned more about the study and provided permission).
  • This research study is testing medication strategies for weight loss in individuals with schizophrenia or schizoaffective disorder. Participants will be randomly assigned (like a coin flip) to lorcaserin, lorcserin plus metformin, or placebo. All participants will be offered regular diet and exercise counseling. The study lasts one year.
  • The Translational Medicine Program at the Center for Autism and the Developing Brain is recruiting individuals with autism from 5 17 years of age with an IQ over 70 to participate in our study called aV1ation. The purpose of this study is to test an investigational medicine that blocks a hormone receptor in the brain linked to the control of socialization, stress, anxiety and aggression. We want to see if this medicine is effective as a treatment to help improve social functioning in children with ASD.
  • Previous data suggest some depressed patients act as if their internal biological clock is out of sync with the outside world and re-aligning their clock with the timing of sunlight lessens their depressed mood and accompanying depressive symptoms. This protocol may lead to remission during the first week of treatment while causing minimal problems. Which treatment condition a participant will receive will be determined randomly (i.e., by chance, essentially a computerized flip of a coin).
  • The Center for OCD and Related Disorders and the Institute of Genomic Medicine is conducting a study to look for genetic causes of OCD. Our goal is to look at the genes of individuals with OCD to see if we can identify what may have put those individuals at risk for OCD. Participants will receive a clinical evaluation at no cost, a blood draw (up to 2 tablespoons) and compensation for their time. Significant findings from these genetic tests will be reported back to participants (if they chose to be notified of results).
  • In this research study, you will be fitted with hearing aids that may be fully tuned to improve your hearing (full dose) or may be only partially tuned and not likely to substantially improve your hearing (low dose). You will receive a free hearing aid that will be at full dose at the end of the 12 week study. You will also receive treatment for depression with an FDA approved medication called escitalopram (Lexapro) or duloxetine (Cymbalta).