Current Studies

Here is a list of some of our current studies. For additional studies, please visit RecruitMe.

  • We are seeking adolescents ages 13-17 to participate in a study on anhedonia. Anhedonia is the reduced ability to feel pleasure or enjoy things, and is a key feature of depression and other mental illnesses. If you believe your child is experiencing anhedonia, they may be eligible to participate in this study. If your child participates in this study, we will ask that they answer questions about themselves in an interview with our study team and complete some tasks during an electroencephalogram (EEG) test.
  • The goal of the project is to identify brain signatures associated with obsessive-compulsive disorder (OCD) by comparing brain images of (1) individuals with OCD, (2) individuals without OCD, and (3) siblings of individuals with OCD who do not themselves have the disorder. Eligible participants will be asked questions about their medical and psychiatric history, perform tasks on a computer, and receive a brain scan using Magnetic Resonance Imaging (MRI). The study can be completed in one or two in-person visits.
  • We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. If you participate, you will have two different brain scans (MRI and PET scan). You will also have antidepressant treatment for free. We will then be able to see whether information on the brain scans connects with how people do on the medications. The medications are common, and are not experimental. You will be able to discuss the treatment with Dr. Lan before starting the study to make sure that it is the proper treatment for you.
  • We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. Particularly, we are looking at the importance of inflammation in the process. If you participate, you will have genetic testing and three different brain scans (one MRI and two PET scans). You will also receive an experimental medication for your depression named N-acetyl cysteine (NAC). Please contact us if you are interested in participating.
  • Columbia University Medical Center is presently recruiting individuals who have experienced trauma to participate in an fMRI research study. For your participation, you will receive up to $270 and an opportunity to advance research in the area of trauma and PTSD. This study involves two visits.
  • This research study aims to explore learning and memory in children who have not been diagnosed with any neurological or psychiatric disorders. This study will take place at the New York State Psychiatric Institute in the Washington Heights neighborhood of Manhattan. Participation in this study includes three parts: interviews, games and puzzles, and 1-2 MRI scans. Your child will receive compensation up to $325 in the form of a gift card for participating in this study.
  • Columbia University Medical Center is presently recruiting healthy individuals to participate in an fMRI research study. For your participation, you will receive up to $270 and an opportunity to advance research in the area of trauma and PTSD. This study involves two visits.
  • This study intends to learn more about the symptoms of psychosis and beliefs. The study takes around 2-3 days to complete and involves clinical interviews, clinical chart review, computer tests, and magnetic resonance imaging (MRI) scans.
  • We are currently enrolling individuals with social anxiety disorder to participate in this study. The purpose of this study is to assess whether a brief computer-based research treatment helps improve social anxiety symptoms. For eligible participants, this study will involve a brief, novel research treatment for social anxiety, delivered in 8 or 12 sessions over the course of 4 or 8 weeks. Participants will receive payment for completing study assessments.
  • We are seeking children ages 7 - 12 to participate in a research study on irritability. The study consists of two lab visits. During the first lab visit, we will interview you and your child. During the second lab visit, your child will complete 3 tasks on the computer while electroencephalography (EEG) data are collected. We will also ask you to complete two short surveys 6-months and 12-months from the first lab visit. If your child participates, your family may be compensated up to $120.

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