Current Studies

Here is a list of some of our current studies. For additional studies, please visit RecruitMe.

  • We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. Particularly, we are looking at the importance of dopamine signaling in the process. If you participate, you will have two different brain scans (MRI and PET scan). You will also have treatment for your depression with an FDA approved medication, lurasidone (Latuda). The study is funded by the Columbia University Irving Institute to improve the treatment of bipolar disorder. Please contact us if you are interested in participating.
  • We are trying to understand what causes bipolar disorder and how medications treat bipolar depression. Particularly, we are looking at the importance of inflammation in the process. If you participate, you will have genetic testing and three different brain scans (one MRI and two PET scans). You will also receive an experimental medication for your depression named N-acetyl cysteine (NAC). Please contact us if you are interested in participating.
  • Columbia University Medical Center is presently recruiting individuals who have experienced trauma to participate in an fMRI research study. For your participation, you will receive up to $270 and an opportunity to advance research in the area of trauma and PTSD. This study involves two visits.
  • Columbia University Medical Center is presently recruiting healthy individuals to participate in an fMRI research study. For your participation, you will receive up to $270 and an opportunity to advance research in the area of trauma and PTSD. This study involves two visits.
  • This study intends to learn more about the symptoms of psychosis and beliefs. The study involves clinical interviews, clinical chart review, computer tests, and magnetic resonance imaging (MRI) scans.
  • We are currently enrolling individuals with social anxiety disorder to participate in this study. The purpose of this study is to assess whether a brief computer-based research treatment helps improve social anxiety symptoms. For eligible participants, this study will involve a brief, novel research treatment for social anxiety, delivered in 8 or 12 sessions over the course of 4 or 8 weeks. Participants will receive payment for completing study assessments.
  • This research study aims to identify a distinct pattern of brain abnormalities that underlie OCD by assessing the changes in brain circuits following treatment with cognitive-behavioral therapy (CBT) in children and adolescents. Study Procedures: A free, thorough diagnostic evaluation ~ A full course of CBT (12-16 sessions) at no cost ~ fMRI scans before and after CBT treatment ~ Three months of free follow-up treatment for OCD including medical care. Study evaluations and treatment will be provided at no cost to you.
  • Approximately half of the individuals with Post-traumatic Stress Disorder (PTSD) present with major depressive disorder (MDD). Compared to PTSD alone, patients with comorbid PTSD-MDD demonstrate greater distress and poorer treatment outcome. The goal of this pilot study is to collect preliminary data on the feasibility, safety, and initial efficacy of an integrated therapeutic approach of a combination treatment with PE and Pramipexole, a dopamine agonist, in treating patients suffering with PTSD and Depression. This study includes pre- and post- treatment research MRI Scans.
  • Approximately half of the individuals with Post-traumatic Stress Disorder (PTSD) present with major depressive disorder (MDD). Compared to PTSD alone, patients with comorbid PTSD-MDD demonstrate greater distress and poorer treatment outcome. The goal of this pilot study is to collect preliminary data on the feasibility, safety, and initial efficacy of an integrated therapeutic approach of a combination treatment with PE and Pramipexole, a dopamine agonist, in treating patients suffering with PTSD and Depression. This study includes pre- and post- treatment research MRI Scans.
  • The purpose of this study is to learn more about how individuals with OCD respond to a stress reactivity task. This study may help us to better understand the brain basis of OCD so that we can improve OCD treatments. You will be asked to complete a stress reactivity task and questionnaires about your symptoms and health for compensation of up to $100.

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