Current Studies

Here is a list of some of our current studies. For additional studies, please visit RecruitMe.

  • Principal Investigator

    Alla Landa, PhD
    Why do some individuals continue to experience chronic symptoms of Lyme Disease, such as pain, fatigue, sensory hypersensitivity, and neurocognitive difficulties long after receiving treatment? Through the use of brain imaging (functional MRI) and specific biomarker testing, we hope to gain a better understanding as to why patients develop this persistent, debilitating pain. Based on prior research, we suspect that Lyme disease may change the pattern of an individual's brain activation, making him or her more sensitive to pain than a healthy person.
  • Principal Investigator

    Brian A. Fallon, MD
    Are you suffering from chronic fatigue that began after you were diagnosed and treated with antibiotics for Lyme Disease? This new treatment research study investigates whether disulfiram, commonly known as "Antabuse", has the potential to be used as a treatment option for patients experiencing chronic post-treatment Lyme symptoms. This well-known, FDA approved drug is currently used to help individuals with alcohol dependence resist consumption; however, new scientific research has demonstrated that disulfiram is a potent killer of the Lyme bacteria in the laboratory setting.
  • Principal Investigator

    Joshua T. Kantrowitz, MD
    The purpose of this study is to evaluate the efficacy, safety and tolerability of different doses and durations of TV-46000 given by subcutaneous (under the skin) injection as compared to placebo for use as a potential maintenance in adults with schizophrenia.
  • Principal Investigator

    Laura Mufson, PhD
    Interpersonal Psychotherapy is an effective treatment for adolescents with depression and for adults with PTSD in a recent study. We aim to investigate the use of Interpersonal Psychotherapy for adolescents suffering from PTSD or elevated PTSD symptoms. Participation includes a thorough diagnostic evaluation and a full course of Interpersonal Psychotherapy for Adolescents (IPT-A; 14-16 weeks). If participants have shown reduced PTSD symptoms, they will also receive 3 months of once a month maintenance treatment. All study procedures will be provided at no cost to you.
  • Principal Investigator

    Bret R. Rutherford, MD
    The purpose of this study is to investigate the relationship between aging processes and PTSD, which may help identify novel therapeutic targets to promote healthier aging trajectories for PTSD patients. Chronic PTSD increases mortality risk from medical diseases, promotes aging-associated syndromes such as frailty, and is linked to faster cognitive decline in older adults. One strong possibility is that PTSD leads to these adverse health outcomes by accelerating biological aging in the brain and body.
  • Principal Investigator

    Sandra Comer, PhD
    This 8-week inpatient study seeks to recruit healthy male and female patients who are currently using heroin or non-medically using opioid analgesics. Following screening participants are admitted onto the inpatient unit where they complete testing sessions throughout the inpatient stay. Participants are compensated for each screening visit and for each inpateint day if they enroll in the trial. Total payments will be approximately $6720.
  • The Neurocognition of Language Laboratory is seeking children from 6 12 years of age to participate in a brain study of visual-sensory processing. We will use a technique called electroencephalography (EEG) to measure the brains electrical activity by placing small electrodes that rest on the scalp. EEG is pain-free, safe, and non- invasive. We are looking for children with autism spectrum disorder (ASD) who do not take psychiatric medications and neurotypical children without psychiatric diagnoses.

  • Principal Investigator

    Frances R. Levin, MD
    This study will test a computer-based behavioral intervention to decrease cocaine use. Those who fail to achieve cocaine abstinence after the first 4 weeks while receiving the behavioral treatment will continue the behavioral treatment and be randomly assigned to one of two groups (one group will receive Adderall-XR (MAS-ER) and the other group will receive placebo (an inactive sugar pill)), over the course of 10 weeks. Patients will be asked to come into the clinic for outpatient treatment 3 times per week.
  • Principal Investigator

    Randy P. Auerbach, PhD
    We are seeking adolescents ages 13-17 to participate in a study on anhedonia. Anhedonia is the reduced ability to feel pleasure or enjoy things, and is a key feature of depression and other mental illnesses. If you believe your child is experiencing anhedonia, they may be eligible to participate in this study. If your child participates in this study, we will ask that they answer questions about themselves in an interview with our study team and complete some tasks during an electroencephalogram (EEG) test.
  • Principal Investigator

    Helen Blair Simpson, MD, PhD
    The goal of the project is to identify brain signatures associated with obsessive-compulsive disorder (OCD) by comparing brain images of (1) individuals with OCD, (2) individuals without OCD, and (3) siblings of individuals with OCD who do not themselves have the disorder. Eligible participants will be asked questions about their medical and psychiatric history, perform tasks on a computer, and receive a brain scan using Magnetic Resonance Imaging (MRI). The study can be completed in one or two in-person visits.