Current Studies

Here is a list of some of our current studies. For additional studies, please visit RecruitMe.

  • Principal Investigator:

    Reilly Reyns. Kayser, MD
    The Center for OCD Research at Columbia University Irving Medical Center is seeking individuals with obsessive-compulsive disorder (OCD) to participate in a research study, at no cost to you. This study is investigating the medicinal effects of nabilone for OCD symptoms. Nabilone is a synthetic form of tetrahydrocannabinol (THC), which is one of the active ingredients of marijuana. Participants who enroll will receive study medication or placebo, receive assessments and an MRI scan, and complete behavioral tasks.
  • Principal Investigator:

    Alla Landa, PhD
    Why do some individuals continue to experience chronic symptoms of Lyme Disease, such as pain, fatigue, sensory hypersensitivity, and neurocognitive difficulties long after receiving treatment? Through the use of brain imaging (functional MRI) and specific biomarker testing, we hope to gain a better understanding as to why patients develop this persistent, debilitating pain. Based on prior research, we suspect that Lyme disease may change the pattern of an individual's brain activation, making him or her more sensitive to pain than a healthy person. If we can identify the hyper-activated...
  • Principal Investigator:

    Brian A Fallon, MD
    Are you suffering from chronic fatigue that began after you were diagnosed and treated with antibiotics for Lyme Disease? This new treatment research study investigates whether disulfiram, commonly known as "Antabuse", has the potential to be used as a treatment option for patients experiencing chronic post-treatment Lyme symptoms. This well-known, FDA approved drug is currently used to help individuals with alcohol dependence resist consumption; however, new scientific research has demonstrated that disulfiram is a potent killer of the Lyme bacteria in the laboratory setting. The primary...
  • Principal Investigator:

    Franklin R. Schneier, MD
    We are currently enrolling individuals with social anxiety disorder to participate in this study. The purpose of this study is to assess whether a brief computer-based research treatment helps improve social anxiety symptoms. For eligible participants, this study will involve a brief, novel research treatment for social anxiety, delivered in 8 sessions over the course of 4 weeks. Participants will receive payment for completing study assessments. The study will also assess the effect of research treatments on brain activity using a scan called magnetic resonance imaging (MRI).
  • Principal Investigator:

    Jeffrey M. Miller, MD
    We are seeking patients with obsessive-compulsive disorder (OCD) who are currently experiencing symptoms despite current medication treatment to participate in a research study involving brain imaging and treatment. The goal of this study is to examine whether a type of brain imaging called PET imaging can predict how much benefit patients will have in their OCD symptoms from treatment with an anti-inflammatory medication called celecoxib, which is not FDA approved for this purpose. This study is seeking adults between the ages 18 and 55 years old who have OCD. Eligible participants with OCD...
  • Principal Investigator:

    Joshua Tolkien Kantrowitz, MD
    The purpose of this study is to evaluate the efficacy, safety and tolerability of different doses and durations of TV-46000 given by subcutaneous (under the skin) injection as compared to placebo for use as a potential maintenance in adults with schizophrenia.
  • Principal Investigator:

    Laura Mufson, PhD
    Interpersonal Psychotherapy is an effective treatment for adolescents with depression and for adults with PTSD in a recent study. We aim to investigate the use of Interpersonal Psychotherapy for adolescents suffering from PTSD or elevated PTSD symptoms. Participation includes a thorough diagnostic evaluation and a full course of Interpersonal Psychotherapy for Adolescents (IPT-A; 16 weeks). If participants have shown reduced PTSD symptoms, they will also receive 3 months of once a month maintenance treatment. All study procedures will be provided at no cost to you. Families may receive...
  • Principal Investigator:

    Franklin R. Schneier, MD
    We are currently enrolling individuals with post-traumatic stress disorder (PTSD) to participate in this research study. The purpose of this research study is to evaluate the effectiveness of an investigational medication, brexpiprazole, for PTSD. Eligible participants will be randomly assigned to receive either the study medication or a placebo (sugar pill with no medication), and will complete questionnaires and be monitored by a medical professional throughout the study.
  • Principal Investigator:

    Bret R. Rutherford, MD
    The purpose of this study is to investigate the relationship between aging processes and PTSD, which may help identify novel therapeutic targets to promote healthier aging trajectories for PTSD patients. Chronic PTSD increases mortality risk from medical diseases, promotes aging-associated syndromes such as frailty, and is linked to faster cognitive decline in older adults. One strong possibility is that PTSD leads to these adverse health outcomes by accelerating biological aging in the brain and body. Participants will be asked to attend a total of 3 visits consisting of: an evaluation, an...
  • Principal Investigator:

    Ragy Girgis, MD
    We are conducting a study to understand the brains of people with rheumatoid arthritis. We are recruiting people WITH rheumatoid arthritis between the ages of 18 to 65 to participate in this study at Columbia University Irving Medical Center/New York State Psychiatric Institute. Participation involves: One virtual interview to determine your eligibility (up to 1-2 hours), urine test for substance use, and magnetic resonance imaging (MRI) scan of the brain (up to 30 minutes). As a participant you will receive: Up to $130 over two visits, as well as reimbursement for local transportation. If...

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